LITTLE KNOWN FACTS ABOUT MAKATUSSIN SYROP.

desvenlafaxine will improve the stage or effect of codeine by affecting hepatic enzyme CYP2D6 metabolism. Use Caution/Check. Desvenlafaxine inhibits CYP2D6; with increased desvenlafaxine doses (ie, 400 mg) minimize the CYP2D6 substrate dose by up to 50%; no dosage adjustment essential with desvenlafaxine doses seven consecutive times straight away